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002) or without (p = 0.002). More than half of BMs (58%) from DTC show simultaneous F-FDG and I uptakes which are contrary to the flip-flop phenomenon ( I negative and F-FDG positive). Regardless of I uptake, F-FDG uptake of BMs portends a less favorable therapeutic response and poorer prognosis for patients with DTC. More than half of BMs (58%) from DTC show simultaneous 18F-FDG and 131I uptakes which are contrary to the flip-flop phenomenon (131I negative and 18F-FDG positive). Regardless of 131I uptake, 18F-FDG uptake of BMs portend