https://www.selleckchem.com/pr....oducts/n-butyl-n-4-h
A novel transition-metal-free cascade reaction to synthesize 4-quinolone derivatives has been demonstrated. Michael addition and Truce-Smiles rearrangement are included in this protocol, providing a broad scope of 4-quinolones in moderate-to-excellent yields. This work serves as an example of the use of sulfonamides through Truce-Smiles rearrangement to build heterocyclic compounds under mild conditions.Unprecedented metal-free synthesis of a variety of amines and amides is reported via amination of C(sp3)-H
Like
Comment
Share
