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This process is managed by cell-cell communications between Sertoli cells and building SSCs by autocrine/paracrine and endocrine facets. Additionally it is affected by cells in the interstitial area, such as Leydig cells and peritubular cells. Here, we demonstrate, for the first time, the clear presence of interleukin-34 (IL-34) in Leydig, Sertoli, and peritubular cells and in the premeiotic, meiotic, and postmeiotic cells. Its receptor, colony-stimulating factor-1 (CSF-1), was already s

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