https://pdisignals.com/index.p....hp/chromatin-loop-an
The harmful mechanism and regulatory aftereffects of miRNAs on OTA poisoning in kidney, and particularly the role of HIFα-1/miR-155-5p on OTA-caused ER tension and fibrosis, had been examined in this study. OTA caused hypoxia-like problems such as for example ER tension and fibrosis in HK-2 cells and renal tissues via modulating HIF-1α, that has been followed by regulation of ER stress-related proteins (GRP78 and ATF-4), in addition to fibrosis-related markers (fibronectin, α-SMA, a
Like
Comment
Share
