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We assessed the expressions of glial fibrillary acidic protein (GFAP) and vimentin that play a task in the cyst malignancy and activation associated with astrocytes also as Notch-1 and survivin that be the cause in GBM malignancy after the medications to know just how astrocytes induced GBM medication response. Our outcomes showed that within the co-culture, astrocytes increased GBM survival and resistance after combined drug treatment when compared with mono-cultures. These data restated the
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