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The best performance for detecting LOS was obtained with logistic regression, using the feature set including visibility graph features, with AUROC of 87.7% during the six hours preceding the start of antibiotics, and with predictive potential (AUROC above 70%) as early as 42h before start of antibiotics. These results demonstrate the usefulness of introducing visibility graph indexes in HRV analysis for sepsis prediction in newborns. The method proposed the possibility of non-invasive, real-time monitoring of risk of LOS in a NICU setti
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