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Also, in the A549 cell line, Bax (p value 0.029), Cas-9 (p value 0.00023), miR-34a (p value 0.031), Bcl-2 (p value 0.0076), MMP-13 (p value 0.041), Cas-3 (p value 0.00051) and in MCF-7 cell line Bax (p value 0.0004), Cas-3 (p value 0.0003), Cas-9(p value 0.037), miR-34a (p value 0.005), Bcl-2(pvalue0.0007), mir-21(p value0.016), MMP-13(p value 0.011) and in MDA-231 cell line Bap value0.0001), Cas-3(p value 0.003), Cas-9(p value 0.0004). mir-34a (p value0.0019), Bcl-2(p value0.0023), MMP-13(p value 0.032) have significantly change

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