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05) for grass pollen. Quality of life based on the Rhinoconjunctivitis Quality of Life Questionnaire was significantly improved in patients who received SLIT and remained at a good level after 5 years of observation. During the 5 years of observation after SLIT, there were no significant changes between specific IgG levels and the analysed allergens compared to results just after SLIT. The positive effect obtained after SLIT for grass pollen or house dust mites was sustained for a long period after AIT. The positive effect obtained aft