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rage physicians to further promote HHD. Clinical trial NCT03737578 study registered on November 9, 2018 (Retrospectively registered). Clinical trial NCT03737578 study registered on November 9, 2018 (Retrospectively registered). The translational interest in the intratumoral heterogeneity of hepatocellular carcinoma (HCC) has been increasing. The dismal prognosis of this pathology is linked to the features of the HCC harbouring cancer stem cells (CSC), represented by EpCAM-expression. However, the extent of the impact of intratumoral dist