https://www.selleckchem.com/pr....oducts/buloxibutid.h
Purpose Intraarticular (IA) hyaluronic acid (HA) injection is used to reduce pain and improve mobility in knee osteoarthritis (OA). Little is known about histopathological changes underlying HA efficacy. This study investigated dose-related effects of 1% sodium hyaluronate (BioHA) on knee joint histopathology and pain responses in a medial meniscal tear (MMT) rat model of OA. Methods Following MMT surgery, rats were randomized into treatment groups single IA injection of vehicle, BioHA, or an avian-derived hyaluronic acid (hylan G-F
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