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Finding the Best Medication For ADHD Stimulants are the most commonly prescribed drugs for ADHD. Amphetamines and methylphenidates are among the most frequently prescribed stimulants. Short-acting stimulants begin to work within less than an hour and must be taken multiple times throughout the day. Long-acting stimulants last for up to 16 hours and are taken every day. Your doctor may prescribe antidepressants or other types of drugs "off-label" to treat ADHD symptoms. These are medications that have been approved to treat other conditions, l
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