https://www.selleckchem.com/pr....oducts/AZD2281(Olapa
Thus, the presented approach has proven to have an inevitable potential for biological cell research and therapeutic applications.Despite the widespread use of naphthamide atropisomers in biologically active compounds and asymmetric catalysis, few catalytic methods have succeeded in the enantioselective synthesis of these compounds. Herein, a chiral Brønsted acid (CBA) catalysis strategy was developed for readily scalable dynamic kinetic resolution of challenging ortho-formyl naphthamides with pyrrolylanilines. The chiral axis
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