https://www.selleckchem.com/pr....oducts/2-Methoxyestr
Patients with low ERCC6L expression had significantly longer OS than those with high ERCC6L expression. Knockdown of ERCC6L expression significantly inhibited proliferation, invasion and metastasis in vitro and tumor growth in vivo, and it promoted cell cycle arrest and apoptosis. Mechanistic analyses revealed that PI3K/AKT and NF-κB signaling pathway were inhibited by silencing ERCC6L. These results demonstrate that ERCC6L plays a critical role in HCC progression, and thereby might be a potential therapeutic target for
Like
Comment
Share
