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His parents' and brother's gene evaluation was also done by the next-generation sequencing and verified by Sanger sequencing. Associated literature up to March 2020 was searched in Online Mendelian Inheritance in guy (OMIM), PubMed, CNKI and Wanfang databases with "GNB5" "IDDCA" "LADCI" "intellectual developmental condition with cardial arrhythmia" "language delay and interest deficit-hyperactivity disorder or cognitive disability with or without cardiac arrhythmia" whilst t
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