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Perforations, negative appendectomies, and cases of missed appendicitis by study phase did not differ significantly by study group. Costs did not differ overall by study group. In this study, AppyCDS was not associated with overall reductions in diagnostic imaging; exploratory analysis revealed more appropriate use of imaging in patients with a low pARC score. ClinicalTrials.gov Identifier NCT02633735. ClinicalTrials.gov Identifier NCT02633735. Low-dose intradermal influenza vaccines could be a suitable alternative to full intramuscular

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