https://www.selleckchem.com/JAK.html
Co-administration between warfarin (WF) and Roxb. (Zingiberaceae) (CX) is found in Indonesian patients and need to be evaluated. This study assesses the effect of concomitant administration of CX extract on the pharmacokinetics of WF in rats. Wistar rats were divided into 4 groups ( = 6) and administered with 2% Pulvis Gummi Arabicum (PGA, control), fluconazole (FZ, 6 mg/kg), CX-1 (6 mg/kg) or CX-2 (18 mg/kg BW) for 7 days. For the single-dose study, at the 8th day, WF (1 mg/kg) was administered to all groups and blood samples were taken from 0.25
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