https://www.selleckchem.com/pr....oducts/Temsirolimus.
The main endocrine cell types in pancreatic islets are alpha, beta, and delta cells. Although these cell types have distinct roles in the regulation of glucose homeostasis, inadequate purification methods preclude the study of cell type-specific effects. We developed a reliable approach that enables simultaneous sorting of live alpha, beta, and delta cells from mouse islets for downstream analyses. We developed an antibody panel against cell surface antigens to enable isolation of highly purified endocrine subsets from mouse islets