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Background Although animal studies showed that Follistatin-like 1 (FSTL1) exerts cardioprotective effects against ischemic injury, little is known in humans. We examined whether FSTL1 is secreted in an infarcted myocardium and whether its production is associated with left ventricular (LV) remodeling in survivors of acute myocardial infarction (AMI). Methods and results FSTL1 levels were measured by enzyme-linked immunosorbent assay in plasma collected from the aortic root (AO) and the anterior interventricular vein (AIV) in 93 patients
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