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In this paper, a novel feature selection algorithm for inference from high-dimensional data (FASTENER) is presented. With its multi-objective approach, the algorithm tries to maximize the accuracy of a machine learning algorithm with as few features as possible. The algorithm exploits entropy-based measures, such as mutual information in the crossover phase of the iterative genetic approach. FASTENER converges to a (near) optimal subset of features faster than other multi-objective wrapper methods, such as POSS, DT-forward and FS-SDS, and
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