https://www.selleckchem.com/pr....oducts/pim447-lgh447
Finally, by targeting HosA-dCa9 fusion to pigment gene fwnA, we confirmed that histone deacetylase HosA activated the expression of fwnA, accelerated the synthesis of melanin. Targeted epigenome editing is a promising technology and this study is the first time to apply the epigenetic CRISPR/dCas9 system on regulating the expression of the secondary metabolic genes in A. niger.In the last decades, there has been an increase in impacts on the environment, driven by the industrialization process. As a result, society's social and en
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