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Bhutan implemented a national program for human papillomavirus (HPV) vaccination in 2010 involving girls aged 12 to 18 years and achieving nearly 90% coverage. To estimate HPV vaccine effectiveness in a city in Bhutan. 2 cross-sectional surveys, 2011-2012 and 2018. 2 hospitals in Thimphu, capital of Bhutan. Sexually active women aged 17 to 29 years 1445 participants from the baseline survey and 1595 from the repeated survey. National HPV vaccination program. HPV was assessed in cervical cell samples by using general primer GP5+/GP6+-medi
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