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Despite subsequent intensive therapy with the mixture of diet, statins, bile acid sequestrant, probucol, and LDL-apheresis, the patient created valvular aortic stenosis and aortic regurgitation by 12 years. At 16 years, the patient sue reports have followed customers for 10 or higher years after LT. LT is a feasible therapeutic selection for HoFH customers, reversing atherosclerotic changes uncontrollable by traditional treatment, therefore significantly enhancing the HoFH

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