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There were statistically significant associations between presence of ICACs and periodontitis (OR=4.55), hypertension (OR=3.02), hyperlipidemia (OR=2.87), increasing age (OR=2.24), and the male gender (OR=1.85). Smoking status was not significantly correlated with ICACs. This study revealed that nearly half (45%) of the subjects displayed ICACs on the CBCT images. ICACs are significantly related to the status of chronic periodontitis, age, gender, and CVDs. A more careful review of CBCT scans is highly recommended to detect these calcif