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2 gene, rs55839915. These variants were found to be associated with an increased risk of aEARR, particularly restricted to men [OR 6.09; 95%CI 2.6-14.23 and OR 6.86; 95%CI 2.65-17.81, respectively]. Marginal associations were found at previously studied variants such as SSP1 rs11730582 [OR 0.54; 95%CI 0.34-0.86; p = 0.008], P2RX7 rs1718119 [OR 0.6; 95%CI 0.36-1.01; p = 0.047], and TNFRSF11A rs8086340 [OR 0.6; 95%CI 0.38-0.95; p = 0.024]), found solely in females. Multiple putative genetic variants located at chromosomes X and Y are pote

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