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High-density area EMG (HDsEMG) for the tibialis anterior was evaluated during ramped isometric dorsiflexions at 10, 30, 50 and 70% of maximum voluntary contraction (MVC). MU faculties had been successfully obtained from HDsEMG of 11 youngsters (four feminine) pre- and post-ingestion of 8 mg cyproheptadine or a placebo. Antagonism of 5-HT2 receptors caused a reduction in MU discharge price during steady-state muscle mass activation that was in addition to the amount of contraction intensity [P less th