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n from detrimental ones in mammals. This study identifies deep, phylogenetically conserved commonalities between CNS axon regeneration and other examples of successful tissue regeneration and provides new targets for studying the molecular underpinnings of successful CNS axon regeneration, as well as a guide for distinguishing pro-regenerative injury-induced changes in gene expression from detrimental ones in mammals. Cigarette smoking is an important risk factor for cardiac diseases. In the current study, we sought to assess the effect

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