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rapeutic procedure. But to have a correct and reliable diagnosis, the tissue samples have to be adequately collected and treated. We explore the treatment of bone metastases in advanced non-small cell lung cancer (NSCLC). We reported a 76-year-old female patient, who was diagnosed with NSCLC with bone metastasis eight years ago (stage IVA). Due to unbearable diarrhea, she refused chemotherapy, and we adopted local treatment, including local radiotherapy 50 Gy and bone cement to lumbar spinal metastases, 62 Gy local radiotherapy of primar
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