https://www.selleckchem.com/pr....oducts/defactinib.ht
Since SphK2 is the dominant sphingosine kinase in brain, we propose that the accumulation of sphingadiene-based lipids in SphK2-deficient brains results from the slower catabolism of these lipids, combined with a bottleneck in the catabolic pathway created by the absence of SphK2. We have therefore uncovered a previously unappreciated role for SphK2 in lipid quality control.With the development of technology, the network structure has changed a lot. Many people regard the Internet of Things as the next-generation network structure, w
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