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We focus on the problem of scarcity of annotated training data for nucleus recognition in Ki-67 immunohistochemistry (IHC)-stained pancreatic neuroendocrine tumor (NET) images. We hypothesize that deep learning-based domain adaptation is helpful for nucleus recognition when image annotations are unavailable in target data sets. We considered 2 different institutional pancreatic NET data sets one (ie, source) containing 38 cases with 114 annotated images and the other (ie, target) containing 72 cases with 20 annotated images. The gold sta
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