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How to Calculate TPN: A Step-by-Step Guide Total Parenteral Nutrition (TPN) is a form of feeding that bypasses the digestive system and delivers nutrients directly into the bloodstream. TPN is used when a patient is unable to consume food or absorb nutrients through the digestive system due to a medical condition. provides patients with all the necessary macronutrients, micronutrients, and fluids required for their body's metabolic needs. Calculating TPN requires an understa