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The registration date is October 22, 2013. More than one-third of AF patients included in this study were hospitalized at least once during over 3-year follow-up. The main cause for hospitalization among the elderly patients (≥ 65 years) is non-cardiovascular diseases rather than AF. Multidisciplinary management of comorbidities should be advocated to reduce hospitalization in AF patients older than 65 years old. Clinical Registry http//www.chictr.org.cn/showproj.aspx?proj=5831 . Unique identifier ChiCTR-OCH-13003729. The registration d

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