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Male SD rats were intraperitoneally injected with streptozotocin to induce DM. DM rats were orally administered compound broad-spectrum antibiotics for 2 months. Following the rats had been sacrificed, their particular blood, urine, feces, and renal tissues had been harvested for analyses. We unearthed that weighed against the control rats, DM rats had irregular intestinal microflora, increased plasma acetate levels, increased proteinuria, th
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