https://www.selleckchem.com/pr....oducts/s-gsk1349572.
417 ± 7 g, P less then 0.05) and caloric intake (162 ± 20 vs. 192 ± 9 kcal/kg of body wt, P less then 0.05) compared with males, and leptin infusion reduced BW (-10%) and caloric intake (-62%) similarly in both sexes. In rats with streptozotocin-induced diabetes (n = 5/sex), intracerebroventricular leptin treatment for 7 days completely normalized glucose levels. The same dose of leptin administered intraperitoneally did not alter MAP, HR, glucose levels, or caloric intake in normal or diabetic rats. These results show that leptin'