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1%). Among isolates with the bla -carrying Toronto/Rio plasmid in 2007-2018, a novel genogroup G15576 was predominant (66.7%). Isolates with the TEM-135 β-lactamase were more resistant to ciprofloxacin but were more susceptible to ceftriaxone and tetracycline than isolates with TEM-1. Seven PPNG isolates less susceptible to cefixime possessed the plasmidic bla allele and had mosaic or non-mosaic alterations within PBP2. The proportion of PPNG with the bla -carrying Toronto/Rio plasmid increased during the last 12 years. The increase in P

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