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Phytochemicals may also be effective at targeting VM construction and in addition their principal signaling pathways. Therefore, in this evaluate report, we shown important signaling paths within VM, as well as the phytochemicals that affect these kind of buildings including curcumin, genistein, lycorine, luteolin, columbamine, triptolide, Rome polyphylla, dehydroeffusol, jatrorrhizine hydrochloride, grapes seed proanthocyanidins, resveretrol, isoxanthohumol, dehydrocurvularine, galiellalactone, oxacyclododecindione, brucine, honokiol, ginsenoside Rg3, and al

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