https://www.selleckchem.com/pr....oducts/smoothened-ag
Aurora kinases despite their similarity have distinct roles in the cell cycle, which is regulated by cell-matrix adhesion and growth factors. This study reveals loss of adhesion and re-adhesion to differentially regulate Aurora kinases. AURKB activation that drops on the loss of adhesion recovers on re-adhesion in serumdeprived conditions but not in the presence of serum growth factors. A rapid 30 min serum treatment of serumdeprived cells blocks the adhesion-dependent recovery of AURKB, which negatively correlates wi
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