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Myocardial infarction (MI) incidence often peaks in winter, but it remains unclear how winter temperature affects MI temporally and spatially. We examined the short-term effects of winter temperature on the risk of MI and explored spatial associations of winter MI hospitalizations with temperature and socioeconomic status (area-based index) in Brisbane, Australia. We used a distributed lag non-linear model to fit the association at the city level between population-weighted daily mean temperature and daily MI hospitalizations during 1