https://www.selleckchem.com/pr....oducts/deferoxamine-
Objectives In rheumatoid arthritis (RA) patients, TGF-β exerts a singular effect on lymphocytes, macrophages, and polymorphonuclear leukocytes. Moreover, evidences indicate that TGF-β1 stimulation affects the expression levels of TGF-β receptors. Therefore, we analysed in different leukocyte subpopulations, whether the mRNA abundance of TGFBR2 splice variants might be related to RA. Methods We isolated different leukocyte subpopulations from peripheral blood from 9 healthy control volunteers and 9 RA patients, matched by g