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7 and 2.4 years, and ROI of 27.1% and 42.2%, for Scenario 1 and Scenario 2, respectively. Sensitivity analyses showed that the unit plastic selling price was the most sensitive parameter, followed by the amount of feedstock WPC, and the number of batches.Pathogenic flaviviruses antagonize host cell Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling downstream of interferons α/β. Here, we show that flaviviruses inhibit JAK/STAT signaling induced by a wide range of cytokines beyond interferon, including int

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