https://www.selleckchem.com/pr....oducts/vps34-in1.htm
The most common fusion was the ETV6-NTRK3. Compared to the NTRK-wt group, the NTRK aberration group had more APC and PTPRD aberrations (p0.05). NTRK fusion was also associated with lower tumour mutation burden (TM (p0.05). TP53 and LRP1B mutations were significantly associated with higher TMB (both p0.01), which may be potential markers of immunotherapy. This is the first study to report targeted DNA profiling of Chinese patients with head and neck cancers. As NTRK genetic aberrations are more common in this Chinese popu
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