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Our results showed that Gal-1 had been markedly down-regulated in the samples from symptoms of asthma customers. In vitro research also proved that Gal-1 appearance had been decreased in PDGF-BB-stimulated ASMCs. In addition, Gal-1 overexpression significantly inhibited PDGF-BB-induced ASMCs proliferation and migration, while Gal-1 knockdown exhibits opposite results of Gal-1 overexpression. The PDGF-BB-caused reductions in expressions of α-smooth muscle actin

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