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The center symmetry and mirror symmetry with different side face arrangements in turn manipulate the shape evolution to cubes and bipyramids, respectively. Our study provides a comprehensive understanding of the formation and growth of 2D metal nanomaterials.Due to the importance of the amino ketone motif in synthetic and medicinal chemistry, the number of protocols developed in recent years has considerably increased. This review serves to collate and critically evaluate novel methodologies published since 2011 towards this hi

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