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Therefore, multiplexing detection of tumor-suppressor genes (p16, p21 and p53) could be readily realized by using size-encoded magnetic microbeads pre-functionalized with corresponding probe DNA illustrating the potential of this method in multiplexing bioassay applications. Ion mobility spectrometry is an important rapid analysis method. However, it is difficult to achieve quantitative analysis when spectral peaks overlap. A new method for analyzing ion mobility spectra is presented here. The method achieves quantitative analysis by comb