https://www.selleckchem.com/pr....oducts/Gefitinib.htm
The maximum value (δx 1,3 = 1.21 × 10-2) of the preferential solvation of SE415 by PEG 400 was achieved at x 1 = 0.15. Then, using GastroPlus software, the maximum dissolution, improved in vivo oral absorption, and high regional compartmental absorption (total 99.0%) of SE415 in humans were predicted. Finally, the solubility data were correlated/predicted using various cosolvency models with satisfactory results. Thus, the binary cosolvent system can be a promising approach for enhanced oral absorption in controlling DM and associated
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