https://www.selleckchem.com/pr....oducts/lificiguat-yc
MIF expression was significantly increased, peaking at 1 day after DAI, and MIF was mainly localized in microglial cells and neurons. ISO-1 suppressed neuronal apoptosis, axonal injury, and glial responses and decreased the expression of downstream signaling molecules related to TLR2/4, including ERK, phospho-ERK, NF- B, phospho-NF- B, IL-1 , IL-6, and TNF- . MIF was involved in the neuronal and axonal damage through a TLR-related pathway following DAI. MIF was involved in the neuronal and axonal damage through a TLR-related pat
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