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These controllable drug delivery systems can quickly respond to microenvironmental changes (PH, enzyme, etc.) or external stimuli (photo, heat, magnetic or electric fields). Thus, it is to overcome the side effects by controllable drug delivery systems in vivo. In this article, we summarize the various kinds of stimulus-responsive nanocarriers for cancer therapy and discuss its possibilities and challenges in future application.Introduction Women living with HIV in Canada experience barriers to comprehensive HIV care. We sought to describ