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1 ± 55.6 mL) in comparison to Group B (230.3 ± 65.4 mL). Postoperative ES transfusion was performed on two patients in Group A (6.7%) and six patients in Group B (30%) (p = 0.02). Accordingly, the mean drain withdrawal time in Group A was 3 (2.8-3.; days, and in Group B, this time was 6 (5.0-6. days (p 0.001). Systemic side effects, especially thromboembolism, were not observed in any of the patients. The topical use of TXA in spinal fusion surgery reduced perioperative blood loss. Key Words Blood loss, Thoracolumbar spinal