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The treated patients were between 9 and 76-years old providing information on a full spectrum of patients that require treatment with antihistamines. CONCLUSIONS The presented real-world cases using the second-generation antihistamine, bilastine, demonstrated favorable outcomes for the treated patients. While effectively relieving symptoms, the antihistamine was reported to be safe and well-tolerated. J Drugs Dermatol. 2020;19(2)145-154. doi10.36849/JDD.2020.4835.The interleukin-17 (IL-17) pathway plays a crucial role in the development

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