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This is the first report of a mutation in ficolin- 3 gene in a family with POF. Our findings can lead to the enhancement f genetic databases of patients with POF, specifically for families with high-risk background. Pseudomonas aeruginosa is one of the opportunistic pathogens causing frequent hospital-acquired life-threatening infections in mechanically ventilated patients. The most significant virulence factor of P. aeruginosa is T3SS. PcrV is an important structural protein of the T3SS. In the current investigation, a recombinant scFv
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