https://www.selleckchem.com/pr....oducts/Temsirolimus.
Only 9 models were based on nonparametric approaches. Rifampin was the drug most studied, but only using parametric approaches. The simulations showed that nonparametric approaches improve the error term compared with parametric approaches. More and better models, ideally using nonparametric approaches linked with clear pharmacodynamic goals, are required to optimize anti-TB drug dosing, as recommended in the WHO End TB strategy. More and better models, ideally using nonparametric approaches linked with clear pharmacodynamic goals,
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